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Ophthalmology and Visual Sciences

Kaye dots in a penetrating keratoplasty graft

Kaye dots in a penetrating keratoplasty graft

Category(ies): Cornea, External Disease
Contributor: Jesse Vislisel, MD
Photographer: Carol Chan, CRA

Kaye dots are white punctate epithelial opacities located in the epithelium anterior to the suture line of a corneal graft. The dots represent epithelial cells in various stages of degeneration on histopathology and it has been hypothesized that they may result from an epithelial response to the area of tissue angulation. Kaye dots are not visually significant and do not bear any clinical significance.

References:
  1. Krachmer, Jay H., Mark J. Mannis, and Edward J. Holland. Cornea. St. Louis, Mo: Mosby, 2011.

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