Essential iris atrophy is one of the subtypes of iridocorneal endothelial (ICE) syndrome. In this condition, an abnormally proliferating corneal endothelium grows across the trabecular meshwork and iris to form broad peripheral anterior synechiae (PAS), ectropion uveae, and iris stretch and melt holes. This photograph shows corectopia with a superotemporal iris melt hole in a patient with essential iris atrophy. The patient also had extensive PAS on gonioscopy.
A 54-year-old woman was originally referred to the glaucoma service by the optometry clinic for right pupil dyscoria. Examination originally showed a mild beaten-bronze appearance of the corneal endothelium, peripheral anterior synechiae extending past Schwalbe line, and a slight nasal peaking of the iris which progressed over several years into a horizontal ovoid dyscoria. She developed intraocular hypertension and was treated with one drop of timolol in the morning in the right eye.
Ophthalmic Atlas Images by EyeRounds.org, The University of Iowa are licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License.
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