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Ophthalmology and Visual Sciences

Plexiform neurofibroma

Plexiform neurofibroma

Category(ies): Pathology
Contributor: Meagan Seay, DO and Nasreen Syed, MD

Plexiform neurofibromas are firm, rubbery lesions that may cause a typical S-shaped deformity of the upper eyelid. They are associated with neurofibromatosis type 1.

These lesions are circumscribed and contain spindle-shaped cells arranged in ribbons and cords.