47-year-old female referred for decreased vision left eye(OS)>right eye(OD) and uveitis, both eyes (OU) diagnosed 5 days prior by an outside provider. Anterior segment exam was notable for 2+ cell and flare OU and 2+ vitreous cells OU. Fundus exam demonstrated multiple deep round yellow-white lesions.
Fluorescein angiography was notable for diffuse disc leakage OU. A diagnosis of birdshot choroiditis was made and the patient was treated with oral prednisone with resolution of symptoms. Blood testing was positive for HLA A29.
A 43-year-old woman presented with progressive photophobia, new floaters, and nyctalopia in both eyes. On posterior segment examination at presentation she had optic nerve swelling, perivenular sheathing, an multiple yellow deep choroidal lesions extending radially. She also showed severe diffuse late leakage on fluorescein angiography. The clinical exam and retinal imaging are consistent with the diagnosis of birdshot chorioretinopathy. Subsequent testing for HLA-A29 was positive.
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