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Ophthalmology and Visual Sciences

Involuted choroidal neovascular membrane (CNVM) mimicking a granuloma in pseudoxanthoma elasticum (PXE)

Involuted choroidal neovascular membrane (CNVM) mimicking a granuloma in pseudoxanthoma elasticum (PXE)

Category(ies): Inherited Eye Disease, Retina
Contributor: Jesse Vislisel, MD
Photographer: Randy Verdick, FOPS

Involuted choroidal neovascular membranes (CNVMs) are included in the differential of chorioretinal granulomas.

This photograph shows the appearance of an involuted choroidal neovascular membrane (CNVM) mimicking a granuloma in a patient with pseudoxanthoma elasticum (PXE). The bottom photograph shows the appearance of the CNVM several years earlier while in its active state. Also visible in the photographs are the angioid streaks and peau d'orange fundus appearance which are typical of PXE.

fundus -  appearance of an involuted choroidal neovascular membrane (CNVM) mimicking a granuloma
This photograph shows the appearance of an involuted choroidal neovascular membrane (CNVM) mimicking a granuloma in a patient with pseudoxanthoma elasticum (PXE)
fundus -  appearance of an involuted choroidal neovascular membrane (CNVM) mimicking a granuloma
The appearance of the CNVM several years earlier while in its active state. Also visible in the photographs are the angioid streaks and peau d'orange fundus appearance which are typical of PXE