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Ophthalmology and Visual Sciences

Lisch nodules

Lisch nodules

Category(ies): Glaucoma, Iris, Pediatrics
Contributor: Jesse Vislisel, MD
Photographer: Ed Heffron, Brice Critser, CRA

Lisch nodules are melanocytic hamartomas of the iris, often associated with neurofibromatosis (NF) I. They are usually elevated and tan in appearance. Their incidence in NF1 increases with age and their prevalence raises by about 10% per year of life, up to age 9. These photographs show the various appearances of these nodules in 3 different patients with NF1.

brown eye with lisch nodules
Photos of patient by Brice Critser, CRA
blue eye with lisch nodules
Photos of patient by Brice Critser, CRA
lisch nodules
Photos of patient 3 by Ed Heffron
lisch nodules high magnification
Photos of patient 3 by Ed Heffron