Cuticular drusen, also known as basal laminar drusen, are a type of familial drusen characterized by many clumps of tiny, extramacular drusen. They are strongly associated with the Tyr402His variant of the complement factor H (CFH) gene. Acuity often remains good as long at the drusen remain outside of the fovea.
56 year old female patient with evidence of extramacular drusen 360 degrees in both eyes consistent with cuticular drusen.
OD and OS Widefield color fundus photographs demonstrate 360 degrees of cuticular drusen sparing the macula.
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