Sorsby macular dystrophy is an autosomal dominant condition caused by a mutation in the TIMP3 gene. Patients with this condition typically maintain normal acuity until their 40's when they develop severe, bilateral choroidal neovascular membranes. The macular lesions later have a "pseudo-inflammatory" appearance with geographic atrophy and dense clumps of black pigmentation, as seen in these photographs.
Ophthalmic Atlas Images by EyeRounds.org, The University of Iowa are licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License.
Address
University of IowaLegal
Related Links
