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Ophthalmology and Visual Sciences

White Without Pressure (WWP)

White Without Pressure (WWP)

Category(ies): Retina, Vitreous
Contributor: Eric Chin, MD
Photographer: Toni Venckus, CRA

A 20-year-old male was seen in the Retina Clinic for the possibility of retinitis pigmentosa, both eyes. Unrelated to this, the peripheral exam showed relatively symmetric white patches of retina inferiorly and inferotemporally that were visible without scleral indentation. Scleral depressed exam revealed that the retina was attached, and that there was no other peripheral retinal pathology. The vision and remainder of the exam was otherwise unremarkable.

The exact cause of WWP is unknown. There has been controversy regarding its anatomical location, associated pathology, and its potential association with the development of retinal breaks.[1]

Clinically, a white appearance of the equator and/or peripheral retina seen without scleral indentation. Margins are often sharply demarcated from normal retina.

Frequently misdiagnosed as a retinal detachment or retinal schisis; however, scleral indentation reveals that the retina is apposed to the underlying RPE.

Reports show that OCT corresponds to a distinct hyper-reflectance of the outer retina, likely the elipsoid zone on SD-OCT.[2]

  1. Ryan SJ. Retina. Phildadelphia, PA: Elsevier/Mosby; 2006.
  2. Diaz RI, Sigler EJ, Randolph JC, Rafieetary MR, Calzada JI. Spectral domain optical coherence tomography characteristics of white-without-pressure. Retina. 2014 May;34(5):1020-1. PubMed PMID: 24056529

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